Categories Cancer

HRD Score Did Not Predict Benefit of Platinum Therapy in TNBC

HRD Score Did Not Predict Benefit of Platinum Therapy in TNBC A homologous recombination deficiency (HRD) assay testing for impaired double-strand DNA break repair did not predict pathologic response to preoperative chemotherapy in a randomized trial of women with early-stage triple-negative breast cancer (TNBC) and no known BRCA germline mutation,1 adding to evidence that suggests […]

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Categories Cancer

Markers may predict patient response to immune therapy of cancer

Markers may predict patient response to immune therapy of cancer For many individuals with different types of cancer, immune checkpoint inhibitors can effectively boost their immune system to fight their disease, but not all patients benefit from these medications. Now a team led by investigators at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) […]

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Categories Multiple Myeloma

Trillium Therapeutics Announces Updated Data From Its Ongoing TTI-622 and TTI-621 Dose …

Trillium Therapeutics Announces Updated Data From Its Ongoing TTI-622 and TTI-621 Dose … TTI-622 (SIRPa-IgG4 Fc) completed 8 mg/kg safety assessment in the ongoing dose escalation study in relapsed/refractory lymphoma; now escalating to 12 mg/kg dose level. TTI-622 monotherapy shows 6/18 (33%) objective responses at 0.8 to 8 mg/kg dose levels, including 3/6 (50%) objective […]

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Categories Cancer

Breast cancer type 2 susceptibility protein

Breast cancer type 2 susceptibility protein Sequence statusi: Complete. This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All Feature key Position(s) DescriptionActions Graphical view Length Sequence conflicti 758 S β†’ N in CAA64484 (PubMed:8524414).Curated 1 Sequence conflicti 1761 β€“ 1762 GY β†’ RI in CAA64484 (PubMed:8524414).Curated 2 Sequence conflicti 1767 […]

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Categories Multiple Myeloma

Multiple Myeloma Treatment Market Solid Analyzed Segmentation, Demand, Recent Share …

Multiple Myeloma Treatment Market Solid Analyzed Segmentation, Demand, Recent Share … This detailed report on Multiple Myeloma Treatment market largely focuses on prominent facets such as product portfolio, payment channels, service offerings, applications, in addition to technological sophistication. The report lends versatile cues on market size and growth traits, besides also offering an in-depth section […]

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