Categories Multiple Myeloma

Plasma Cell Disorders/Dyscrasias – Multiple Myeloma Pathology Review

Plasma Cell Disorders/Dyscrasias – Multiple Myeloma Pathology Review Plasma cell dyscrasias are a monoclonal proliferation of plasma cells that produce a clonal immunoglobulin protein (i.e., monoclonal gammopathies or paraproteinemias). They are derived from malignant B lymphocytes. Common plasma cell dyscrasias include multiple myeloma and Waldenström’s macroglobulinemia. Plasma cell disorders are a group of hematological malignancies […]

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Categories Multiple Myeloma

Dr. Lesokhin Discusses Exciting Advances in Multiple Myeloma

Dr. Lesokhin Discusses Exciting Advances in Multiple Myeloma Alexander M. Lesokhin, MD, assistant attending, Department of Medicine and Myeloma Service, Memorial Sloan Kettering Cancer Center, discusses some of the exciting advancements currently happening in the field of multiple myeloma. According to Lesokhin, a lot of the excitement is around chimeric antigen receptor (CAR) T-cells, though […]

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Categories Multiple Myeloma

Expert Session – 11.10.2021 – Newly Diagnosed Multiple Myeloma (NDMM)

Expert Session – 11.10.2021 – Newly Diagnosed Multiple Myeloma (NDMM) During this FREE 2-hour Expert Session on newly diagnosed multiple myeloma, our faculty will provide myeloma patients—and their families and caregivers—with a clear understanding of multiple myeloma, including how it is diagnosed and treated and will take questions during 2 dedicated Q&A sessions.

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Categories Multiple Myeloma

MGUS and Smoldering Myeloma | Memorial Sloan Kettering

MGUS and Smoldering Myeloma | Memorial Sloan Kettering Ola Landgren, Chief of Memorial Sloan Kettering’s Myeloma Service, explains disorders that predispose a person to myeloma and how they are treated. Learn about MSK: https://www.mskcc.org CONNECT WITH MSK Facebook: http://facebook.com/sloankettering Twitter: http://twitter.com/sloan_kettering Instagram: http://instagram.com/sloankettering Request an appointment at MSK by calling 800-525-2225 or online at: https://www.mskcc.org/appointments/request-appointment

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Categories Multiple Myeloma

Once Weekly Selinexor, Carfilzomib, and Dexamethasone (XKd) in Heavily Pretreated Multiple Myeloma

Once Weekly Selinexor, Carfilzomib, and Dexamethasone (XKd) in Heavily Pretreated Multiple Myeloma Background of the Study: Exportin 1 (XPO1) mediates the nuclear export and functional inactivation of tumor suppressor proteins (TSPs), is associated with poor prognosis in MM, and contributes to proteasome inhibitor (PI) and immunomodulatory drug (IMiD) resistance. Selinexor (SEL) is a novel, oral, […]

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Categories Multiple Myeloma

CAR T-Cell Therapy for Multiple Myeloma

CAR T-Cell Therapy for Multiple Myeloma Keith Stewart, MB, ChB; Saad Z. Usmani, MD; Thomas G. Martin, MD; Sagar Lonial, MD; Ivan M. Borrello, MD; and Gareth Morgan, MD, PhD, highlight trials that are reviewing the potential use of chimeric antigen receptor T-cell therapy that targets the protein, B-cell maturation antigen in multiple myeloma.

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