Cancer Immunotherapeutics Center
Protocol: 19-052
Title: A Phase 1/2 First-in-human Study of the Safety and Efficacy of IMC-C103C as a Single Agent and in Combination with Atezolizumab in HLA-A*0201-positive Patients
Protocol: 19-063
Title: Phase 1/1b Study of the Safety of TTX-030 as a Single Agent and in Combination with Pembrolizumab or Chemotherapy in Patients with Lymphoma or Solid Tumor
Protocol: 19-065
Title: A Phase 1b Study of INCMGA00012 in Combination With Other Therapies in Patients With Advanced Solid Tumors (POD1UM-102)
Protocol: 19-066
Title: A Phase 1, First-in-Human, Open-Label, Dose Escalation Study of MGD013, A Bispecific DART® Protein binding PD-1 and LAG-3 in Patients with Unresectable or Metastatic Neoplasms
Protocol: 19-074
Title: A Phase 1/1b Open-label, Dose-escalation and Dose-expansion Study of TPST-1120 as a Single Agent or in Combination with Systemic Anti-Cancer Therapies in Subjects with Advanced Solid Tumors
Protocol: 19-078
Title: ADaptiVe Biomarker Trial that InformS Evolution of Therapy (ADVISE)
Protocol: 19-079
Title: A Phase 1, First-in-Human, Open-Label, Dose Escalation and Cohort Expansion Study of MGD019, a Bispecific DART® Protein Binding PD-1 and CTLA-4 in Patients with Unresectable or Metastatic Neoplasms
Protocol: 19-081
Title: “A Phase I Study of BMS-986301 Monotherapy and Combination Therapy with Nivolumab and Ipilimumab in Participants with Advanced Solid Cancers”
Protocol: 19-095
Title: A Phase 1/1b multicenter study to evaluate the humanized anti-CD 73 antibody, CPI-006, as a single agent, in combination with CPI-444, and in combination with pembrolizumab in adult subjects with advanced cancers
Protocol: 19-097
Title: A Phase Ib/II study of ARRY-614 plus either nivolumab or ipilimumab in advanced melanoma, renal cell carcinoma, and solid tumors
Protocol: 19-098
Title: A Phase 1 Multiple-Dose Study to Evaluate the Safety and Tolerability of XmAb®23104 in Subjects with Selected Advanced Solid Tumors (DUET-3)
Protocol: 19-099
Title: A Phase 1 Multiple-Dose Study to Evaluate the Safety and Tolerability of XmAb®22841 Monotherapy and in Combination with Pembrolizumab in Subjects with Selected Advanced Solid Tumors (DUET-4)
Protocol: 19-100
Title: A Phase 1 Multiple Dose Study to Evaluate the Safety and Tolerability of XmAb®20717 in Subjects with Selected Advanced Solid Tumors (DUET-2)
Protocol: 19-101
Title: A Phase 1, Open-label Study of ASP9801, an Oncolytic Virus, Administered by Intratumoral Injection in Patients with Advanced/Metastatic Solid Tumors
Protocol: 19-112
Title: Human Leukocyte Antigen Typing and Tumor Antigen Expression Profiling
Protocol: 19-113
Title: Phase 1 study evaluating genetically modified autologous T cells expressing a T-cell receptor recognizing a cancer/germline antigen in patients having solid tumors including but not limited to non-small cell lung cancer or head and neck squamous cell carcinoma (ACTengine IMA201-101)
Protocol: 19-114
Title: Phase 1 study evaluating genetically modified autologous T cells expressing a T-cell receptor recognizing a cancer/germline antigen in patients with recurrent and/or refractory solid tumors (ACTengine® IMA202-101)
Protocol: 19-115
Title: Phase 1 study evaluating genetically modified autologous T cells expressing a T-cell receptor recognizing a cancer/germline antigen in patients with recurrent and/or refractory solid tumors (ACTengine® IMA203-101)
Protocol: 19-123
Title: A Phase 1a/1b Dose-escalation Study of Intravenously Administered SB 11285 Alone and in Combination with Atezolizumab in Patients with Advanced Solid Tumors
Protocol: 19-124
Title: “A Multicenter, Open-Label, Dose Escalation Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect on Pharmacokinetics of the DNA-PK Inhibitor M3814 in Combination with Avelumab with and without Palliative Radiotherapy in Participants with
Selected Advanced Solid Tumors”
Protocol: 19-160
Title: An Open-Label, Multicenter Phase 1/1b Study of Intratumorally Administered STING Agonist E7766 in Subjects with Advanced Solid Tumors or Lymphomas – INSTAL-101
Protocol: 19-161
Title: A Phase 1, Open-label, Multicenter Study of SYNB1891 Administered by Intratumoral Injection to Patients with Advanced/Metastatic Solid Tumors and Lymphoma Alone and in Combination with Atezolizumab
Protocol: 19-169
Title: A Phase 1, Open-Label, Dose-Escalation and Expansion Study of IK-175, an Oral Aryl Hydrocarbon Receptor (AHR) Inhibitor in Patients with Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma
Protocol: 19-177
Title: Phase I/II Open-Label, Safety and Preliminary Efficacy Study of MRx0518 In Combination with Pembrolizumab In Patients with Advanced Malignancies Who Have Progressed On PD-1/PD-L1 Inhibitors
Protocol: 19-199
Title: Phase 1 Study of BDC-1001 as a Single Agent and in Combination with Pembrolizumab in Patients with Advanced and HER2 Expressing Solid Tumors
Protocol: 19-203
Title: A Phase 1 Study of SGN-TGT in Subjects with Advanced Malignancies
Protocol: 20-015
Title: A phase 1, open-label, multiple-ascending dose study to investigate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of KD033 in subjects with metastatic or locally advanced solid tumors
Protocol: 20-025
Title: A Phase 1/2 First-in-Human Study of the Safety and Efficacy of IMC-F106C as a Single Agent and in Combination with Checkpoint Inhibitors in HLA-A*02:01-Positive Participants with Advanced PRAME-Positive Cancers
Protocol: 20-040
Title: Phase 1/2 Study of RTX-240 Monotherapy
Protocol: 20-051
Title: A phase 1 study of SGN-CD228A in select advanced solid tumors
Protocol: 20-061
Title: An Open-label, Dose Escalation, Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-676 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced or Metastatic Solid Tumors
Protocol: 20-062
Title: Phase 1/1b Study to Evaluate the Safety and Activity of TTX-030 (Anti-CD39) in Combination with Budigalimab and/or Chemotherapy in Subjects with Advanced Solid Tumors
Protocol: 20-080
Title: “A Phase 1/2 Study of NM21-1480 (Anti-PDL-1/Anti-4-1BB/Anti-HSA Tri-Specific Antibody) in Adult Patients with Advanced Solid Tumors
“
Protocol: 20-081
Title: A Phase 1/1b, Open-Label, Dose Escalation and Expansion Study of SBT6050 in Subjects with Advanced Solid Tumors Expressing HER2
Protocol: 20-086
Title: An open-label study of ALPN-202 in subjects with advanced malignancies
Protocol: 20-088
Title: A Phase 1a/1b Open-label, Dose-Escalation and Expansion Study of TPST-1495 as a Single Agent and in Combination with Pembrolizumab in Subjects with Solid Tumors
Published at Fri, 06 Nov 2020 02:54:24 +0000