The hallmarks of cancer are also the hallmarks of wound healing [unable to retrieve full-text content] In this Review, we highlight how tissue repair and cancer share cellular and molecular processes that are regulated in a wound but misregulated in …Published at Tue, 08 Sep 2020 18:00:00 +0000
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HRD Score Did Not Predict Benefit of Platinum Therapy in TNBC A homologous recombination deficiency (HRD) assay testing for impaired double-strand DNA break repair did not predict pathologic response to preoperative chemotherapy in a randomized trial of women with early-stage triple-negative breast cancer (TNBC) and no known BRCA germline mutation,1 adding to evidence that suggests […]
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Markers may predict patient response to immune therapy of cancer For many individuals with different types of cancer, immune checkpoint inhibitors can effectively boost their immune system to fight their disease, but not all patients benefit from these medications. Now a team led by investigators at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) […]
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Trillium Therapeutics Announces Updated Data From Its Ongoing TTI-622 and TTI-621 Dose … TTI-622 (SIRPa-IgG4 Fc) completed 8 mg/kg safety assessment in the ongoing dose escalation study in relapsed/refractory lymphoma; now escalating to 12 mg/kg dose level. TTI-622 monotherapy shows 6/18 (33%) objective responses at 0.8 to 8 mg/kg dose levels, including 3/6 (50%) objective […]
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The Multiple Myeloma Patient Journey Understanding the journey of a myeloma patient can sometimes be daunting. Find out more about the cancer that affects over 7,500 Canadians. For more information visit www.myeloma.ca .
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